USE IN SPECIFIC POPULATIONS

Foster City, CA: Gilead Sciences, Inc; 2014 Dec.

Neurologic, psychological, and aggressive disturbances with sildenafil.

• Sildenafil tablets 125 mg should not be used by women.
• Always read the medication guide thoroughly.
• Overdose can cause serious health issues.
• Sildenafil can cause a sudden decrease in blood pressure.
• Inform your doctor of all medications you take.
• Sildenafil may improve erectile function in men with ED.
• Do not use sildenafil more than once per day.
• Effects can vary based on individual health.

Gilad R, Lampl Y, Eshel Y, Sadeh M. Tonic-clonic seizures in patients taking sildenafil. Nonarteritic ischemic optic neuropathy developing soon after use of sildenafil: a report of seven new cases. Tadalafil associated with anterior ischemic optic neuropathy.

• Sildenafil is sometimes used off-label for other health issues.
• Its interaction with blood thinners should be monitored.
• Men with retinitis pigmentosa should avoid sildenafil.
• Always inform healthcare providers about all treatments.
• Use sildenafil in conjunction with a healthy lifestyle.
• Avoid unnecessary medication to prevent side effects.
• Be aware of potential drug interactions with sildenafil.
• Proper storage maintains medication efficacy over time.

Bollinger K, Lee MS.

Drug Interactions for Viagra

Available on the World Wide Web at: Abman SH, Kinsella JP, Rosenzweig EB, et al. Implications of the U.S. Food and Drug Administration Warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension. The Top 100 Drug Interactions: A Guide to Patient Management. includes table of CYP450 and drug transporter substrates and modifiers (appendices).

FAQs About Sildenafil Dosage

Indianapolis, IN: Lilly ICOS, LLC; 2011 Oct. Indianapolis, IN: Lilly ICOS, LLC; 2007 Jan. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2014 Aug. Hall MCS, Ahmad S. Interaction between sildenafil and HIV-1 combination therapy.

6.2 Postmarketing Experience

Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Research Triangle Park, NC: ViiV Healthcare; 2013 Apr. Research Triangle Park, NC: GlaxoSmithKline; 2005 Nov. Princeton, NJ: Bristol-Myers Squibb Company; 2014 Jun. Recurrent visual field defect and ischemic optic neuropathy associated with tadalafil rechallenge. 503A pharmacies compound products for specific patients whose prescriptions are sent by their healthcare provider. 503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices. Our team of experts has the answers you're looking for. A clinical pharmacist cannot recommend a specific doctor. Because we are licensed in all 50 states*, we can accept prescriptions from many licensed prescribers if the prescription is written within their scope of practice and with a valid patient-practitioner relationship. Each injectable IV product will have the osmolarity sildenafil citrate drug listed on the label located on the vial. Given the vastness and uniqueness of individualized compounded formulations, it is impossible to list every potential compound we offer. To inquire if we currently carry or can compound your prescription, please fill out the form located on our Contact page or call us at (877) 562-8577. We source all our medications and active pharmaceutical ingredients from FDA-registered suppliers and manufacturers.

VIAGRA is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg, and 100 mg of sildenafil for oral administration. VIAGRA is indicated for the treatment of erectile dysfunction.

However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity.

Altitude illness

Princeton, NJ: Bristol-Myers Squibb Company; 2003 Sep. Quinidex Extentabs (quinidine sulfate extended-release tablets) package insert. Richmond, VA: A.H. Robbins Company; 2000 Sept. Ranexa (ranolazine extended-release tablets) package insert.

Is Viagra dosage based on age or weight?

Foster City, CA: Gilead Sciences, Inc. 2013 Dec. Research Triangle Park, NC: Bertek Pharmaceuticals; 2003 Feb. South San Francisco, CA: Actelion Pharmaceuticals US, Inc.; 2007 Feb. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2008 Jun.

Regional issues

Rifampin and rifabutin drug interactions: an update. Morris Plains, NJ: Parke-Davis; 1999 June. NOTE: Troglitazone was removed from the US market in response to FDA concerns in March 2000. NOTE: As of May 2000; Propulsid has only been available in the United States via an investigational limited access program to ensure proper patient screening and pres New York, NY: Danco Laboratories, LLC; 2009 Apr. Menlo Park, CA: Corcept Therapeutics Incorporated; 2013 Jun. VIAGRA may be taken with or without food.

VIAGRA was shown to potentiate the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors such as organic nitrates or organic nitrites in any form is therefore contraindicated [see CONTRAINDICATIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. When VIAGRA is co-administered with an alpha-blocker, patients should be stable on Sections or subsections omitted from the full prescribing information are not listed. alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at 25 mg [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY].

5.7 Priapism

Interactions of sildenafil and tacrolimus in men with erectile dysfunction after kidney transplantation. Combined oral therapy with sildenafil and doxazosin for the treatment of non-organic erectile dysfunction refractory to sildenafil monotherapy. Effects of grapefruit juice on the pharmacokinetics of sildenafil. Goldmeier D. Prolonged erections produced by dihydrocodeine and sildenafil.

Full Text Sources

Research Triangle Park, NC: GlaxoSmithKline; 2001 Aug. Casper F, Petri E. Local treatment of urogenital atrophy with an estrodiol-releasing vaginal ring: a comparative and a placebo-controlled multicenter study. Int Urogynecol J Pelvic Floor Dysfunct 1999;10:171-6 Adalat CC (nifedipine extended-release tablets) package insert. West Haven, CT: Bayer Pharmaceuticals Corporation; 2010 Aug. The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a 48 hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY]. Consider a starting dose of 25 mg in patients > 65 years, patients with hepatic impairment (e.g., cirrhosis), and patients with severe renal impairment (creatinine clearance <30 mL/minute) because administration of VIAGRA in these patients resulted in higher plasma levels of sildenafil [see Use In Specific Populations and CLINICAL PHARMACOLOGY].

• Sildenafil tablets are classified as phosphodiesterase inhibitors.
• They are quick-acting but effects vary by individual.
• Avoid taking with other erectile dysfunction medications.
• Liver or kidney impairment may require dose adjustments.
• Do not use sildenafil during sexual activity if unadvised.
• Safe sexual activity involves knowing your health status.
• Window for maximum effectiveness is around 1 hour before.
• Avoid excessive physical exertion after taking sildenafil.

VIAGRA is supplied as blue, rounded diamond shaped film-coated tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil. Tablets are debossed with “VIAGRA” on one side and “VGR 25”, “VGR 50” or “VGR 100” on the other to indicate the dosage strengths. VIAGRA (sildenafil citrate) is supplied as blue, rounded diamond shaped film-coated tablets containing sildenafil citrate equivalent to the nominally indicated amount of sildenafil and debossed on the obverse and reverse sides as follows: Store at 25°C (77°F); excursions permitted to 15-30°C (59- 86°F) [see USP Controlled Room Temperature]. Distributed by: Viatris Specialty LLC, Morgantown, WV 26505 U.S.A. Revised: Nov 2023 The following are discussed in more detail in other sections of the labeling: Prolonged Erection and Priapism [see WARNINGS AND PRECAUTIONS] Effects on the Eye [see WARNINGS AND PRECAUTIONS] Hypotension when Co-administered with Alpha-blockers or Anti-hypertensives [see WARNINGS AND PRECAUTIONS] Adverse Reactions with the Concomitant Use of Ritonavir [see WARNINGS AND PRECAUTIONS] Combination with other PDE5 Inhibitors or Other Erectile Dysfunction Therapies [see WARNINGS AND PRECAUTIONS] Effects on Bleeding [see WARNINGS AND PRECAUTIONS] Counseling Patients About Sexually Transmitted Diseases [see WARNINGS AND PRECAUTIONS] The most common adverse reactions reported in clinical trials (≥ 2%) are headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness, and rash. VIAGRA was administered to over 3700 patients (aged 19-87 years) during premarketing clinical trials worldwide. In placebo-controlled clinical studies, the discontinuation rate due to adverse reactions for VIAGRA (2.5%) was not significantly different from placebo (2.3%). Adverse Reactions Reported by ≥2% of Patients Treated with VIAGRA and More Frequent than Placebo in Fixed-Dose Phase II/III Studies * When VIAGRA was taken as recommended (on an as-needed basis) in flexible-dose, placebo-controlled clinical trials of two to twenty-six weeks duration, patients took VIAGRA at least once weekly, and the following adverse reactions were reported: Adverse Reactions Reported by ≥2% of Patients Treated with VIAGRA and More Frequent than Placebo in Flexible-Dose Phase II/III Studies * The following events occurred in <2% of patients in controlled clinical trials; a causal relationship to VIAGRA is uncertain.

17. Patient Counseling Information

Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2014 Apr. Foster City, CA: Gilead Sciences, Inc; 2014 Sept. Princeton, NJ: Bristol-Myers Squibb Company; 2015 Jan. Prezcobix (darunavir and cobicistat) tablets package insert. Interaction of sildenafil and indinavir when co-administered to HIV-patients.

Recreational use

North Chicago, IL: AbbVie Inc; 2015 Jan. Research Triangle Park, NC: ViiV Healthcare Company; 2013 May. Princeton, 150mg sildenafil for sale NJ: Bristol-Myers Squibb Company; 2014 May. Walters JS, Woodring JH, Stelling CB, Rosenbaum HD: Salicylate-induced pulmonary edema. Balon R.

Patient resources

Fluvoxamine-induced erectile dysfunction responding to sildenafil. Whitehouse Station, NJ: Merck & Co., Inc.; 2007 Nov. North Chicago, IL: AbbVie, Inc.; 2015 Jan. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2008 Dec. Indianapolis, IN: Eli Lilly and Company; 2003 Nov. Reported events include those with a plausible relation to drug use; omitted are minor events and reports too imprecise to be meaningful: Body as a Whole: face edema, photosensitivity reaction, shock, asthenia, pain, chills, accidental fall, abdominal pain, allergic reaction, chest pain, accidental injury. Respiratory: asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, sputum increased, cough increased. Skin and Appendages: urticaria, herpes simplex, pruritus, sweating, skin ulcer, contact dermatitis, exfoliative dermatitis. Analysis of the safety database from controlled clinical trials showed no apparent difference in adverse reactions in patients taking VIAGRA with and without antihypertensive medication.