SC 20 Pill: white, round, 7mm

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Sildenafil (Revatio) will not be safe for you to take. Take nitrates, such as nitroglycerin or isosorbide mononitrate (Monoket) Take riociguat (Adempas) or other sGC stimulators You’ve probably heard of Viagra being commonly referred to as “the little blue pill”, and its distinctive blue colour is synonymous with the treatment of erectile dysfunction (ED). Sildenafil, the active ingredient in Viagra, is manufactured in a variety of colours, but most commonly in either blue or white. But does the colour and shape of your pill make a difference in the effectiveness of the treatment? When Viagra was first approved as a treatment for ED in 1998, it was marketed as “the little blue pill”.

• Some sildenafil tablets are coated to improve taste and ease swallowing.
• Sildenafil should not be used if allergic to citrate compounds.
• Cost savings on generic sildenafil make it accessible to more users.
• The medication requires no special diet, but avoid fatty foods close to ingestion.
• Sildenafil may cause a modest drop in blood pressure temporarily.
• Do not share prescribed sildenafil with others; it is tailored to individual health.
• Inform your doctor of all medications and health conditions before use.
• Sildenafil may have different effects based on age and health status.
• The medication has been available in various formulations for convenience.
• The effectiveness may vary, and some users might need dose adjustments.
• Always keep sildenafil tablets out of reach of children and pets.

The small, blue, diamond-shaped pill was patented by Viagra, meaning that both its appearance and active ingredient were exclusive to Viagra and couldn’t be copied by other manufacturers.

After Pfizer’s patent for Viagra expired in 2013, sildenafil (the active ingredient in Viagra) was made more widely available for manufacturing by other companies. Nowadays, many manufacturers continue to make sildenafil as a blue-coloured pill, but it also comes in a variety of other shapes and colours, and is sometimes manufactured as a white pill. This is commonplace, and, as with many types of generic medication, you may find that the appearance of your pills sometimes changes each time you order them.

• Sildenafil tablets are classified as phosphodiesterase inhibitors.
• White sildenafil tablets are available by prescription only.
• They should not be used with nitrates due to risk of dangerous drops in blood pressure.
• Certain medications may interact with sildenafil, including antibiotics and antifungals.
• The tablets are designed to last approximately 4-6 hours.
• Overuse can lead to adverse effects like dizziness or vision changes.
• Sildenafil helps men with erectile dysfunction achieve and maintain erections.
• The medicine is not an aphrodisiac and requires sexual stimulation.
• The tablets should be stored in a cool, dry place away from children.
• Beware of counterfeit sildenafil tablets sold online.
• Always verify the legitimacy of the medication before use.

However, don’t worry; the active ingredients and effectiveness of the treatment remain the same. The main difference between sildenafil and Viagra is that Viagra is branded, and sildenafil is the generic, or unbranded, version of it. As both sildenafil and Viagra contain the same active ingredient, sildenafil citrate, they are both effective treatments for men with ED. All generic medication has to contain the same active ingredient to ensure it works in the same way as its brand-name equivalent. Branded medication is often more expensive than generic medication. Any new brand-name medication will pitch the price relative to the amount of initial research needed to develop and prepare the treatment for marketing approval.

Generic medication can typically be 20-90% cheaper than its brand-name equivalent because of this. The other important factor in pricing is competition: as sildenafil is widely available for manufacture, the price is more competitive (and therefore cheaper).

5.8 Priapism

Any new brand-name medication will pitch the price relative to the amount of initial research needed to develop and prepare the treatment for marketing approval. Generic medication can typically be 20-90% cheaper than its brand-name equivalent because of this. The other important factor in pricing is competition: as sildenafil is widely available for manufacture, the price is more competitive (and therefore cheaper). A 2019 study was conducted into the effectiveness of generic medication, which found that there was no difference between how generic sildenafil tablet manforce 50 mg and brand-name medication works. Even though generic sildenafil is unbranded, it is still an effective treatment for ED and works in the same way as Viagra.

What should I know about sildenafil before taking it?

Both Viagra and sildenafil are considered effective treatments for ED. The colour and shape of the pill have no impact on how effective the treatment is. The main difference between generic medication, such as sildenafil, and brand-name medication, such as Viagra, is the purchase price and the appearance of the pill. If you are a consumer or patient please visit this version. See full prescribing information for SILDENAFIL TABLETS.SILDENAFIL tablets, for oral useInitial U.S.

How is sildenafil supplied (dosage forms)?

Approval: 1998INDICATIONS AND USAGEAdultsSildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay sildenafil oral strips clinical worsening. (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day. (2.1)DOSAGE FORMS AND STRENGTHSTablets: 20 mg (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. A 2019 study was conducted into the effectiveness of generic medication, which found that there was no difference between how generic sildenafil tablet manforce 50 mg and brand-name medication works. Even though generic sildenafil is unbranded, it is still an effective treatment for ED and works in the same way as Viagra. Both Viagra and sildenafil are considered effective treatments for ED. The colour and shape of the pill have no impact on how effective the treatment is. The main difference between generic medication, such as sildenafil, and brand-name medication, such as Viagra, is the purchase price and the appearance of the pill. If you are a consumer or patient please visit this version. See full prescribing information for SILDENAFIL TABLETS.SILDENAFIL tablets, for oral useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay sildenafil oral strips clinical worsening. (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day. (2.1)DOSAGE FORMS AND STRENGTHSTablets: 20 mg (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. (7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. (5.6)Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information.See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 4/2024 Sildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. Adults: 20 mg three times a day. Vasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs.

Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. Use with strong CYP3A inhibitors: Not recommended. Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors.

8.2 Lactation

(5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. (7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. (5.6)Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information.See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 4/2024 Sildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening.

Jet lag research

Adults: 20 mg three times a day. Vasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises.

Before taking sildenafil,

Use with strong CYP3A inhibitors: Not recommended. Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information. See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling. Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information. See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling. Table of Contents FULL PRESCRIBING INFORMATION: CONTENTS*1 INDICATIONS AND USAGE2 DOSAGE AND ADMINISTRATION2.1 Recommended Dosage in Adults3 DOSAGE FORMS AND STRENGTHS4 CONTRAINDICATIONS5 WARNINGS AND PRECAUTIONS5.1 Hypotension5.2 Worsening Pulmonary Vascular Occlusive Disease5.3 Epistaxis5.4 Visual Loss5.5 Hearing Loss5.6 Combination with other PDE-5 Inhibitors5.7 Priapism5.8 Vaso-occlusive Crisis in Patients with Pulmonary Hypertension Secondary to Sickle Cell Disease6 ADVERSE REACTIONS6.1 Clinical Trials Experience6.2 Post-marketing Experience7 DRUG INTERACTIONS8 USE IN SPECIFIC POPULATIONS8.1 Pregnancy8.2 Lactation8.4 Pediatric Use8.5 Geriatric Use8.6 Patients with Hepatic Impairment8.7 Patients with Renal Impairment10 OVERDOSAGE11 DESCRIPTION12 CLINICAL PHARMACOLOGY12.1 Mechanism of Action12.2 Pharmacodynamics12.3 Pharmacokinetics13 NONCLINICAL TOXICOLOGY13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility14 CLINICAL STUDIES16 HOW SUPPLIED/STORAGE AND HANDLING17 PATIENT COUNSELING INFORMATION*Sections or subsections omitted from the full prescribing information are not listed. 1 INDICATIONS AND USAGE AdultsSildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets.

Key takeaways:

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Sildenafil (Revatio) will not be safe for you to take. Take nitrates, such as nitroglycerin or isosorbide mononitrate (Monoket) Take riociguat (Adempas) or other sGC stimulators You’ve probably heard of Viagra being commonly referred to as “the little blue pill”, and its distinctive blue colour is synonymous with the treatment of erectile dysfunction (ED). Sildenafil, the active ingredient in Viagra, is manufactured in a variety of colours, but most commonly in either blue or white. But does the colour and shape of your pill make a difference in the effectiveness of the treatment?

Dosage for pulmonary arterial hypertension (PAH)

When Viagra was first approved as a treatment for ED in 1998, it was marketed as “the little blue pill”. The small, blue, diamond-shaped pill was patented by Viagra, meaning that both its appearance and active ingredient were exclusive to Viagra and couldn’t be copied by other manufacturers. After Pfizer’s patent for Viagra expired in 2013, sildenafil (the active ingredient in Viagra) was made more widely available for manufacturing by other companies. Nowadays, many manufacturers continue to make sildenafil as a blue-coloured pill, but it also comes in a variety of other shapes and colours, and is sometimes manufactured as a white pill. This is commonplace, and, as with many types of generic medication, you may find that the appearance of your pills sometimes changes each time you order them.

How does sildenafil work (mechanism of action)?

However, don’t worry; the active ingredients and effectiveness of the treatment remain the same. The main difference between sildenafil and Viagra is that Viagra is branded, and sildenafil is the generic, or unbranded, version of it. As both sildenafil and Viagra contain the same active ingredient, sildenafil citrate, they are both effective treatments for men with ED. All generic medication has to contain the same active ingredient to ensure it works in the same way as its brand-name equivalent. Branded medication is often more expensive than generic medication. Sildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health liquid sildenafil citrate Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)].

other ED treatments

Known hypersensitivity to sildenafil or any component of the tablet. 5 WARNINGS AND PRECAUTIONS 5.1 HypotensionSildenafil citrate has vasodilatory properties, resulting in mild and transient decreases in blood pressure. Before prescribing sildenafil citrate, carefully consider whether patients with certain underlying conditions could be adversely affected by such vasodilatory effects (e.g., patients on antihypertensive therapy or with resting hypotension [blood pressure less than 90/50], fluid depletion, severe left ventricular outflow obstruction, or autonomic dysfunction). Monitor blood pressure when co-administering blood pressure lowering drugs with sildenafil citrate.5.2 Worsening Pulmonary Vascular Occlusive DiseasePulmonary vasodilators may significantly worsen the cardiovascular status of patients with pulmonary veno-occlusive disease (PVOD). Since there are no clinical data on administration of sildenafil citrate to patients with veno-occlusive disease, administration of sildenafil citrate to such patients is not recommended. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage in AdultsOral DosageThe recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. The recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)]. 4 CONTRAINDICATIONS Sildenafil tablets are contraindicated in patients with:Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension [see Warnings and Precautions (5.1)].Concomitant use of riociguat, a guanylate cyclase stimulator. Phosphodiesterase-5 (PDE-5) inhibitors, including sildenafil, may potentiate the hypotensive effects of riociguat.Known hypersensitivity to sildenafil or any component of the tablet. Hypersensitivity, including anaphylactic reaction, anaphylactic shock and anaphylactoid reaction, has been reported in association with the use of sildenafil.

How much does Sildenafil (Revatio) cost?

Table of Contents FULL PRESCRIBING INFORMATION: CONTENTS*1 INDICATIONS AND USAGE2 DOSAGE AND ADMINISTRATION2.1 Recommended Dosage in Adults3 DOSAGE FORMS AND STRENGTHS4 CONTRAINDICATIONS5 WARNINGS AND PRECAUTIONS5.1 Hypotension5.2 Worsening Pulmonary Vascular Occlusive Disease5.3 Epistaxis5.4 Visual Loss5.5 Hearing Loss5.6 Combination with other PDE-5 Inhibitors5.7 Priapism5.8 Vaso-occlusive Crisis in Patients with Pulmonary Hypertension Secondary to Sickle Cell Disease6 ADVERSE REACTIONS6.1 Clinical Trials Experience6.2 Post-marketing Experience7 DRUG INTERACTIONS8 USE IN SPECIFIC POPULATIONS8.1 Pregnancy8.2 Lactation8.4 Pediatric Use8.5 Geriatric Use8.6 Patients with Hepatic Impairment8.7 Patients with Renal Impairment10 OVERDOSAGE11 DESCRIPTION12 CLINICAL PHARMACOLOGY12.1 Mechanism of Action12.2 Pharmacodynamics12.3 Pharmacokinetics13 NONCLINICAL TOXICOLOGY13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility14 CLINICAL STUDIES16 HOW SUPPLIED/STORAGE AND HANDLING17 PATIENT COUNSELING INFORMATION*Sections or subsections omitted from the full prescribing information are not listed. 1 INDICATIONS AND USAGE AdultsSildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. Sildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health liquid sildenafil citrate Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)]. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage in AdultsOral DosageThe recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. The recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)].

Your expert team

4 CONTRAINDICATIONS Sildenafil tablets are contraindicated in patients with:Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension [see Warnings and Precautions (5.1)].Concomitant use of riociguat, a guanylate cyclase stimulator. Phosphodiesterase-5 (PDE-5) inhibitors, including sildenafil, may potentiate the hypotensive effects of riociguat.Known hypersensitivity to sildenafil or any component of the tablet. Hypersensitivity, including anaphylactic reaction, anaphylactic shock and anaphylactoid reaction, has been reported in association with the use of sildenafil. Sildenafil tablets are contraindicated in patients with: Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension [see Warnings and Precautions (5.1)]. Phosphodiesterase-5 (PDE-5) inhibitors, including sildenafil, may potentiate the hypotensive effects of riociguat. Sildenafil tablets are contraindicated in patients with: Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension [see Warnings and Precautions (5.1)]. Phosphodiesterase-5 (PDE-5) inhibitors, including sildenafil, may potentiate the hypotensive effects of riociguat. Known hypersensitivity to sildenafil or any component of the tablet. 5 WARNINGS AND PRECAUTIONS 5.1 HypotensionSildenafil citrate has vasodilatory properties, resulting in mild and transient decreases in blood pressure. Before prescribing sildenafil citrate, carefully consider whether patients with certain underlying conditions could be adversely affected by such vasodilatory effects (e.g., patients on antihypertensive therapy or with resting hypotension [blood pressure less than 90/50], fluid depletion, severe left ventricular outflow obstruction, or autonomic dysfunction). Monitor blood pressure when co-administering blood pressure lowering drugs with sildenafil citrate.5.2 Worsening Pulmonary Vascular Occlusive DiseasePulmonary vasodilators may significantly worsen the cardiovascular status of patients with pulmonary veno-occlusive disease (PVOD). Since there are no clinical data on administration of sildenafil citrate to patients with veno-occlusive disease, administration of sildenafil citrate to such patients is not recommended.